Introduction: Understanding the prevalence and distribution of the hepatitis C virus
(HCV) is crucial for the development of effective prevention and control strategies,
given its significant impact on global public health. The objective of this study was
to examine the seroprevalence of HCV among blood donors in Kabul and assess the
possible gender-based variations in infection rates.
Materials and Methods: This study analyzed blood donor records from the central
blood bank in Kabul, including both male and female donors, from January to
December 2023. HCV screening was performed using ELISA testing, and the data
were analyzed using SPSS to determine HCV prevalence and investigate genderbased differences in infection rates.
Results: In this study, 59 out of 15,080 individuals (0.39%) tested positive for HCV
infection. Among the HCV-positive cases, 81.5% were male and 18.6% were
female. The majority of infected males (64.4%) were in the 30-39 age range. A
significant proportion of HCV-positive patients had no formal education (69.5%)
and were unemployed (61.0%). Additionally, the majority of HCV-positive patients
reported a low monthly income (66.1%).
Discussion: The study found a low prevalence of HCV infection (0.39%) among the
participants, with the highest rates observed in the 30-39 age group. Socioeconomic
factors, such as lack of education, unemployment, and low income, were associated
with HCV infection. Targeted interventions are needed to address gender disparities,
age-specific risks, and socioeconomic determinants to improve prevention and
control strategies for HCV in Kabul’s blood donor population and enhance overall
population health.